الفهرس | Only 14 pages are availabe for public view |
Abstract Hepatocellular carcinoma (HCC) is among the most common malignancies worldwide. Liver biopsy, considered as the 2gold standard3 for evaluating liver fibrosis, has carried some drawbacks. Currently transient elastography (Fibroscan) is considered as a non invasive method for measuring liver stiffness and detecting liver fibrosis. To evauate the role of fibroscan in predicting the outcome of hepatocellular carcinoma ablation. Prospective study including 100 Egyptian patients with hepatocellular carcinoma. Child-pugh class was calculated, alpha feto protein, triphasic CT abdomen, upper endoscopy and fibroscan were done before hepatocellular carcinoma ablation. Triphasic CT abdomen and fibroscan were done 3 months post ablation. Higher liver stiffness values were observed post HCC ablation (32.2+13.6) especially among patients who were subjected to TACE with liver stiffness percentage change 18+15.9 SD. Patients with portal hypertension and splenomegaly had high liver stiffness values whether pre ablation or post ablation. Higher post ablation liver stiffness was observed among those with incomplete HCC ablation. Liver stiffness increases after HCC ablation especially among those who were subjected to TACE. Post ablation liver stiffness was higher among patients with incomplete HCC ablation than those with complete ablation. We believe that liver stiffness can predict incomplete ablation of the HCC even before doing imaging modalities |