الفهرس 
Effect of mandibular incisor versus first premolars extraction on improvement of facial profile in class III malocclusion adults : A systematic review
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Abstract
Background: To extract lower incisor or lower first premolars in adults with Class III malocclusion is a well conflict in the field of orthodontics. Searching the current orthodontic literature resulted in a controversial opposing results regarding the effect of orthodontic extraction on the soft tissue profile, so the question remains unanswered. Objective: To perform a systematic review to quantify the amount of soft tissue changes measured in cephalograms in adults orthodontics patients who have Class III malocclusion and undergone camouflage treatment. Search Strategy: Electronic databases were searched up to March 2015 in (CENTRAL- Cochrane register of controlled trials, PubMed, Embase, DopPHER). Grey literature was also searched electronically through Google Scholar. Hand searching was done in high impact factor journals in the field (AJODO, CJO, The Angle Orthodontist). Email alert for PubMed and google scholar were set and monitored until March 2015. Citations of all the included studies were also checked manually for relevance. Language was restricted to English. selection criteria: The following criteria were met for study selection: a controlled human trial on a group of adult patients receiving orthodontic extraction of lower incisor compared to a group of extraction lower first premolars in Class III malocclusion. Studies that involved growing patients, orthopedic fixed or removable functional appliances or combined orthodontic and surgical treatment were excluded. Studies with no soft measurements on cephalometric head film were not taken before and after treatment were also excluded