الفهرس 
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Abstract
Aim of the study: In vivo study that was conducted to assess the degree of candida colonization on maxillary single dentures fabricated from two different denture base materials one of them was fabricated
from rapid heat cured acrylic resin and the other fabricated from conventional heat cured acrylic resin modified with titanium dioxide nanoparticles. Seventeen patients with completely edentulous maxilla were randomly selected according to inclusion and exclusion criteria, each patient received two dentures made of rapid heat cured acrylic denture base and modified conventional heat cured acrylic denture base with titanium dioxide nanoparticles then candida samples were taken from the surface of oral mucosa at the crest of the ridge using sterile cotton swabs.
Results: Statistical analysis was performed using SPSS 20®1, Graph Pad Prism®2 and Microsoft
Excel 20163. Data was represented as mean and standard deviation for quantitative data, as
presented in (9) tables and (6) graphs. Data were explored for normality by using Shapiro Wilk and Kolmogorov Smirnov normality test which revealed that all data is parametric data (P-value > 0.05).
Accordingly, comparison between two groups was performed by Independent t test, while
comparison between before and after was performed using Paired t -test. Moreover, percentage of change was calculated using the following formula
Were V1: CFU value before denture insertion.
V2; CFU after 1 month from denture insertion.
In this study we concluded that: addition of titanium dioxide nanoparticles will decrease candida colonization on dentures. While in comparison the rapid heat cured acrylic resin have more affinity to retain the candida increasing its colonization.