الفهرس 
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Abstract
This study was conducted to evaluate the effect of modified heat-cured acrylic resin with titanium nanoparticles on candidal growth. Forty completely edentulous male patients with no history of denture-wearing participated in this study. All the selected patients were re-habilitated by mucosa-supported complete dentures.
The 40 edentulous patients were divided into two groups, GID (control group) contained 20 edentulous patients who received conventional heat-cured acrylic dentures without any modification. GIID contained the same number of patients who received modified nano titanium-heat-cured acrylic resin dentures. Dentures in both groups were constructed with the same materials and following the same construction procedures. The only difference was adding 2% per weight of nano titanium particles to acrylic resin powder for GIID.
Before denture insertion and after denture insertion by 45 days, saliva samples and swab samples were collected from both groups to assess Candida albicans count. The saliva samples were obtained by the Concentrated Oral Rinse technique for both groups.
Before denture insertion, the swab sample was obtained from the palatal mucosa of the upper arch for both. Denture specimens were collected by swabbing for both groups after insertion for 45 days from the upper denture fitting surface and the palatal mucosa (after the follow-up period). A germ tube test was done to identify the candida albicans from another candida species under a light microscope.
The results of this study revealed statistically significant, less candida albicans growth on heat-cured acrylic resin dentures modified with nano titanium particles compared with conventional heat-cured ones.
Conclusion
Based on obtained results and within the limitations of this study, it can be concluded that the addition of 2% per weight of nano titanium dioxide particles to acrylic resin denture bases decreases Candidal growth.
Recommendation
Based on the results of this study, it is recommended to add nano titanium dioxide particles to the acrylic resin denture base during denture construction to decrease Candidal growth.