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العنوان
Retrospective analysis comparing the outcome of lobectomy, segmentectomy and wedge resections in Stage IA non-small cell lung cancer /
المؤلف
El-Gamal, Islam Farouk Gomaa.
هيئة الاعداد
مشرف / خالد سعد الدين كراره
مشرف / منير محمود زعربان
مشرف / حازم فلوح
مشرف / أحمد أنور سعد
الموضوع
Cardiothoracic Surgery.
تاريخ النشر
2022.
عدد الصفحات
31 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الطب (متفرقات)
تاريخ الإجازة
8/12/2022
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Cardiothoracic Surgery
الفهرس
Only 14 pages are availabe for public view

from 67

from 67

Abstract

Lung cancer is the second most common cause of cancer worldwide and the first leading cause of cancer death in the USA among both men and women. Lung cancer is typically diagnosed at advanced stages (III and IV) and carries a high mortality rate, with a 5-year survival rate of only 18%.
The surgical management of NSCLC continues to evolve. Surgery is considered the treatment of choice in functionally operable patients with resectable early-stage NSCLC. Until the results of other randomized trials provide evidence to the contrary, lobectomy should be considered the standard of care for early-stage NSCLC.
There is an increasing trend towards parenchymal sparing sub-lobar resections for early-stage lung cancer, especially in selected patient groups, compromised and elderly. Multiple studies have shown comparable survival to lobectomy.
The aim of this study was to compare the outcome lobectomy, segmentectomy and wedge resections in treating stage IA non-small cell lung cancer patients.
This study included a retrospective comparative analysis of 659 lung cancer patients who underwent lung resections (lobar and sub-lobar: segmentectomy and wedge resection) in Heartlands hospital, University hospitals of Birmingham, England for an early-stage disease IA (T1a/T1b -N0-M0) non-small-cell lung cancer during a 5-year period between 2010 till 2015, based on the 7th lung cancer TNM classification and staging system, followed by a post-resection surveillance program for 5-years period, using the data from the Lung Cancer Registry of the Heartlands thoracic surgery unit and the regional lung cancer MDTs in West-midland.