الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
A series of novel Schiff base complexes were prepared by interacting N-(benzothiazol-2-yl)-3-oxo-3-(2-(3-phenylallylidene)hydrazineyl)propanamide (H2BTOPP) ligand with various divalent metal ions of Co(II), Ni(II) and Cu(II). The separated compounds are elucidated by using several spectroscopic techniques. Based on, IR, 1H-NMR, and 13C-NMR analysis the H2BTOPP acted as mono-negative tri-dentate/tetra-dentate and bi-negative tri-dentate with metal ions. Also, the UV-Visible, magnetic, and ESR measurements confirm the geometrical structures of the prepared complexes which exhibit octahedral geometry. SEM was subjected to the Schiff base ligand and its complexes to provide a microscopic approach to the surface or near-surface region of a specimen, in addition to clarifying the extent of the change in the ligand surface morphology as a result of the formation of metal complexes. Also, the thermal stability of the synthesized complexes was discussed through (TGA/DTA) techniques. Moreover, computational simulation through (DFT/GGA/RPBE) was applied to the molecular skeleton of all compounds associated with the evaluation of some characters (EHOMO, ELUMO, binding energy, dipole moment, MEP).Moreover, different applications are used to support the sight of coordination included in cyclic voltammetry studies which clarified the strong impact of H2BTOPP ligand on the electrochemistry of Cu2+ solution and some kinetic and thermodynamic parameters were evaluated such as (stability constant and Gibbs free energy). Finally, all samples were screened for anti-bacterial against (Bacillus subtilis and Escherichia coli), anti-fungal against (Candida albicans), antioxidant, MTT cytotoxicity, and DNA binding studies to predict the biological activity of the synthesized compounds showing that [Cu(HBTOPP)(OAc)(H2O)].2H2O complex exhibited high biological activity values compared to the other complexes and also outperforms the H2BTOPP ligand.