الفهرس 
Pathophysiology
Covid -19Only 14 pages are availabe for public view
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Abstract
Smmbary The first cases of COVID_ 19 were reported in the Wuhan district,China in December 2019 causing a global outbreak of a novel disease. The disease has affected almost all countries and was declared as a pandemic the World Health organization in March 2020 and there are more than 624 million confirmed cases worldwide with more than 6.5 million deaths as of 23 October 2022.Both diabetes and COVID_19 affect each other, the effect of diabetes on COVID_19 appears in the following: patients with diabetes have a higher risk for infection and severe form of the disease, and showed higher levels of white blood cells (WBC), C-reactive protein (CRP), procalcitonin, creatinine and D-dimer, while The level of lymphocytes was lower in patients with diabetes. Radiological findings including chest CT images were worse in diabetic patients with COVID_19 than in COVID_19 patients only. Before admission, poor glycemic control, as indicated by HbAlc concentrations, was associated with a high risk of mortality. At the time of admission, uncontrolled hyperglycemia acts as predictor of worse CT chest imaging. During hospitalization, hyperglycemia during treatment in hospital has worse prognosis for patients with COVID-19, the mortality rate was higher in those with diabetes. While the effect of COVID_19 on diabetes appears in the following: it can induce a diabetic state or worsen hyperglycemia due to acute impairment of insulin secretion, reduced insulin sensitivity, destruction of.