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Abstract The most common electronic nicotine delivery system is electronic cigarettes. Most of electronic cigarettes consist of a battery and electric heater used to aerosolize a liquid to produce vapor which the user inhales. Poly methyl methacrylate comes in contact with a variety of foods and beverages of different temperatures, as a result, it is prone to absorbing a variety of pollutants, altering its physical structure and appearance. Also, conventional cigarettes smoking resulted in increase of the surface roughness of acrylic resin. Aim of the study: This study aimed to investigate the effects of electronic cigarettes smoking on color stability and surface roughness of acrylic resin. Material and methods: This study was in vitro study in which sixty specimens of CAD/CAM acrylic resin was exposed to aerosols which were flavored and non-flavored with nicotine content (0 mg, 6 mg and 12 mg). A portable suction machine was modified to simulate smoking in vivo. Each specimen was exposed to 20 cycles of aerosol released by a single ECIG device using the smoking chamber. Spectrophotometer was used to measure the color change of the specimens. Surface roughness was quantitatively analyzed using a profilometer and qualitatively analyzed under scanning electron microscope (SEM). Results: No significant difference in color change found between groups exposed to flavorless e-liquid, while a significant difference found between flavored 0 mg. nicotine and 12 mg. nicotine groups (P = 0.002). Also, a significant difference found between flavored 6 mg. nicotine and 12 mg. nicotine groups (P = 0.002). According to Two Way ANOVA, both flavor and nicotine contents have a significant effect on color change (P <0.0001). There was a significant difference in surface roughness between group exposed to flavorless e-liquid with 6 mg. nicotine and control group (p=0.001) and between 12 mg. nicotine and control group (p=0.014).Also, There was a significant difference in surface roughness between group exposed to flavored e-liquid with 6 mg. nicotine and control group (p=0.034) and between 12 mg. nicotine and control group (p=0.016). Conclusion: Exposure to flavored and non-flavored ECIG aerosol of different nicotine concentrations has a significant effect on the color and surface roughness of denture acrylic resin. Higher concentrations of flavored nicotine had visually perceptible color changes and were deemed clinically unacceptable. Also, ECIG aerosols of 6 mg. and 12 mg. either flavored or non-flavored increased the surface roughness of acrylic resin significantly. |