الفهرس 
Fentanyl-midazolam versus Ketamine-midazolam induction of anesthesia in septic shock
AbstractOnly 14 pages are availabe for public view
 |  | from | 86 |  |  |
| | | from | 86 | | |
Abstract
Ketamine has been reported as an induction anesthetic with a sympathomimetic activity that increases heart rate, cardiac output, and arterial blood pressure (ABP) in patients with intact autonomic nervous system; however, the hemodynamic response to ketamine in unstable cardiovascular conditions is not clear. Most of the studies investigating ketamine in unstable patients were either invitro or animal studies. Ketamine was associated with stable hemodynamic profile when used for induction and maintenance of anesthesia in animal models of hemorrhagic shock and septic shock; whilst, it exerted direct dose-dependent negative inotropic effect in both failing and non-failing human cardiac muscles in vitro