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Abstract Purpose: To compare the efficacy of inferior oblique myectomy versus graded recession in improving inferior oblique over-action in two distinct entities: patients with primary and patients with secondary inferior oblique over-action. Setting: Research Institute of Ophthalmology and Abo Elreesh children hospital, Cairo university. Design: Prospective comparative interventional study. Methods:This chart reviewed 60 patients with inferior oblique overaction both primary and secondary types that had inferior oblique weakening surgery done between 2012-2017. Results: This study compromises 60 patients with IOOA; the 60 patients were divided into two groups primary and secondary; 40 (66.7%) patients had primary IOOA; 20 (50%) of them underwent IO myectomy and the other 20 (50%) underwent IO graded recession and 20 (33.3%) patients had secondary IOOA; 10 (50%) of them underwent IO myectomy and the other 10 (50%) underwent IO graded recession.both IO myectomy and graded recession were equally effective in eliminating abnormal head posture and correcting associated pattern whereas in correcting the degree of IOOA IO myectomy was superior to graded IO recession; as90% of patients were fully corrected and 10% were under-corrected following IO myectomy compared to 25% full correction, 65% under-correction and 10% overcorrection following graded IO recession. Conclusions: Both IO myectomy and graded recession were equally effective in eliminating abnormal head posture and correcting associated pattern whereas in correcting the degree of IOOA IO myectomy was superior to graded IO recession. Financial disclosure: No one has a financial or proprietary interest in any material or method mentioned |