الفهرس 
Neurocognitive Outcome Assessment In Patients With Perioptic Meningiomas Operated By The Pterional Versus The Frontotemporal Epidural Approach: A Randomized Controlled Double Blinded Clinical Trial
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Abstract
Background: Meningioma is the most common benign primary brain tumor and their surgical excision is developing rapidly with emerging of new outcomes to assess the surgical excision such as neurocognitive outcome. Objective: Cognitive functions of the patients became an important parameter to evaluate the outcome of intracranial meningioma surgery. The aim of this prospective study is to compare postoperative and preoperative cognitive functions of the patients after meningioma excision by 2 different approaches. Design of the study: Randomized controlled double blinded clinical trial. Randomization done by computer generated tables to allocate patients in the 2 groups. Setting: Cairo university hospitals. Participants: 45 participants with perioptic meningiomas, 41 fulfilled the inclusion criteria. Intervention: In the 1st group, tumor excision done with peeling of the lateral wall of the cavernous sinus, while in the 2nd group tumor excision done without peeling of the lateral wall of the cavernous sinus. Main outcome measures: neurocognitive status of the patients was measured by MoCA-B test 3-7 days preoperative and 7-10 days postoperative. Follow up of the patients after 6 months will be carried on. Results: After exclusion of 4 cases (1 refused operation, 2 with severe visual affection and 1 had severe affected orientation), the remaining 41 cases were allocated to the 2 arms of the study. 22 cases allocated to 1st group, 2 of them died. 19 cases allocated to the 2nd group, 2 of them died