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العنوان
Analytical study of some drugs containing amide group /
الناشر
Sara Abdelbaset Abdelaal Galal ,
المؤلف
Sara Abdelbaset Abdelaal Galal
هيئة الاعداد
باحث / Sara Abdelbaset Abdelaal Galal
مشرف / Hala Elsayed Zaazaa
مشرف / Eman Saad Hassan Elzanfaly
مشرف / Enas Abdelhakim Amer
تاريخ النشر
2017
عدد الصفحات
184 P. ;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Analytical Chemistry
تاريخ الإجازة
26/6/2018
مكان الإجازة
جامعة القاهرة - كلية الصيدلة - Analytical Chemistry
الفهرس
Only 14 pages are availabe for public view

from 227

from 227

Abstract

Part I: General introduction and literature review: This part includes: Introduction about amide functional group and discussion about the chemical structures, properties, pharmacological actions of the selected drugs in this thesis. Literature review on different methods of analysis for the studied drugs. Part II: Determination of oxetacaine in presence of its degradation products: This part includes four sections: Section A: Forced degradation study of oxetacaine. Section B: TLC-densitometric method for the determination of oxetacaine in presence of its hydrolytic and oxidative degradation products. Section C: High performance liquid chromatographic method (HPLC) for the determination of oxetacaine in presence of its hydrolytic and oxidative degradation products. Section D: first derivative of ratio spectra and ratio difference spectrophotometric methods for the determination of oxetacaine in presence of its hydrolytic and oxidative degradation products. Part III: chromatographic methods for determination of E-crotamiton in presence of its Z-isomer. This part includes two sections: Section A: High performance liquid chromatographic method (HPLC) for the determination of E-crotamiton in presence of its Z-isomer. Section B: Gas chromatographic method (GC) for the determination of E-crotamiton in presence of its Z-isomer