الفهرس 
Incidence and impact of acute cardio-renal syndrome on acute coronary syndromes
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Abstract
Background Acute cardio-renal syndrome (CRS-1) is one of the deleterious adverse outcome in acute coronary syndrome (ACS). Objectives Our study is focusing on the incidence and impact of CRS-1 on ACS regarding course of the disease, mortality and length of stay in intensive care unit (ICU). Methodology This is a retrospective cohort study of patients of ACS with or without CRS-1 involving 210 consecutive patients admitted to Critical Care department {u2013} Cairo University over a year from 1 June 2013 to 31 May 2014 Results41.9% of all study population (88/210) had CRS-1 and were of longer ICU stay and more association with other adverse outcomes especially hyponatremia and mechanical ventilation. All mortality cases (10.5%; 22/210) were CRS-1. CRS-1 predictors were: history of hypertension and dyslipidemia, Killip{u2019}s class {u2265}{u2161}, acute myocardial infarction (AMI), higher serum creatinine level on admission, K+ and random blood sugar and lower Na+ values. Persistent kidney injury (KI) predictors were higher heart rate, K+ level and Na+. Contrast induced-acute kidney injury (CI-AKI) and late AKI (after 48 hours of admission) were found, also, as risk factors for persistent KI. Conclusion CRS-1 is a frequent complication of ACS patients. It has a fatal impact on ACS regarding length of ICU stay, adverse outcomes and mortality. History of hypertension and dyslipidemia, AMI, Killip{u2019}s class {u2265}{u2161}, higher serum creatinine level on admission, K+ and random blood sugar and lower Na+ values were found to be risk factors for CRS-1. Persistent KI predictors were higher HR, K+ level and Na+. CIAKI and late AKI (after 48 hours of admission) were found, also, as risk factors for persistent KI