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Abstract Background: Magnesium acts as a cofactor of more than 300 enzymes particularly of enzymes responsible for phosphate transfer and regulates calcium ion movement in smooth muscle cells, which has an important role maintaining cardiac contractility and peripheral vascular tone. The objectives of this study are to investigate the incidence of hypomagnesemia in critically ill children , to identify precipitating factors that could affect magnesium level and to determine its effect on prognosis. Methods: There were 100 children who admitted to the ICU at Fayoum Teaching Hospital from March 1st, 2019 to November 30th, 2019. They were prospectively analyzed excluding Children who received magnesium products within the last 24 hours and children with known congenital renal magnesium wasting (e.g., Bartter’s syndrome and Gitelaman’s syndrome). Results: Percentage of hypomagnesaemia children was 3% and hypermagnesaemia was 40 % at admission. Serum magnesium level has no statistical significant associated with mortality. We investigate other electrolytes sodium and potassium which were routinely assessed in PICU and we found hat sodium level was higher in non survived children than who were survived with statistical significant as P-value>0.026. Conclusion: we cann’t consider serum magnesium is predictive of mortality alone while incorporation of other electrolytes level like sodium is more predictive of mortality than magnesium. key words: magnesium , mortality, pediatric intensive care units |