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العنوان
Assessment of quality of life by Functional Independence Score in Hemophilia in Assiut University Hospital /
المؤلف
Tony, Shymaa Saber.
هيئة الاعداد
باحث / شيماء صابر توني
مشرف / أسامة أحمد ابراهيم
مناقش / أحمد فراج ثابت
مناقش / هوايدا عبد الحكيم
الموضوع
Hemophilia.
تاريخ النشر
2023.
عدد الصفحات
89 p. ;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب
الناشر
تاريخ الإجازة
29/3/2022
مكان الإجازة
جامعة أسيوط - كلية الطب - Clinical Hematology Unit
الفهرس
Only 14 pages are availabe for public view

from 102

from 102

Abstract

The assessment of joint health is one of the most important goals in haemophilia care. The functional Independence Score in Haemophilia (FISH) score is a useful tool for the clinical evaluation of joint affection in the developing countries for its ease of use and applicability. In this study, we aimed at evaluating the quality of life of adult patients with haemophilia by means of the FISH score and assessing its relation to disease severity. Another aim is to minimise joints’ damage by raising patients’ awareness about the importance of rehabilitation. This cross sectional study included adult patients with haemophilia presenting at the Internal Medicine Department, Assiut University Hospital, Faculty of Medicine, Assiut University. The most commonly affected joints were the weight-bearing large joints (knees, elbows, ankles) and this was associated by a lower FISH score in patients having affection of these joints. The average FISH score was 21.11 ± 4.5. The FISH score was slightly lower in severe haemophilia compared to mild-moderate disease; however; this difference did not mount to statistical significance. The total FISH score showed a significant positive correlation with the factor activity level. However, in a multivariable regression model, the independent predictors were the APTT as well as the types of joints affected. A significant decline in the functional ability was observed in haemophilia patients having disease affecting the knee and elbow joints. The squatting was significantly reduced in patients with severe haemophilia. 1- Early and regular physiotherapy is highly recommended to improve quality of life. 2- Prophylactic factor administration regularly can improve quality of life.