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العنوان
Phytochemical Screening and Biological Activity Assessment of Moltkiopsis ciliata Plant Extracts /
المؤلف
Ramadan, Marwa Rabee Fathi Abdel-Hak,
هيئة الاعداد
مشرف / Mamdouh Abdel-Mogib Mohamed
مشرف / Mohamed Abdel-Moniem Mahmoud
مشرف / Amal Mahmoud Youssef Moustafa
مناقش / Mamdouh Abdel-Mogib Mohamed
الموضوع
spectrum of compound.
تاريخ النشر
2022.
عدد الصفحات
151 p. ;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Multidisciplinary
تاريخ الإجازة
26/12/2022
مكان الإجازة
جامعة بورسعيد - كلية العلوم ببورسعيد - Chemistry
الفهرس
Only 14 pages are availabe for public view

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from 151

Abstract

Methanolic extract of the aerial parts of Moltkiopsis ciliata (Forssk.) (Boraginaceae) was obtained and successively fractionated into four main fractions (hexane fraction, methylene chloride fraction, ethyl acetate fraction and butanol fraction).
The two non-polar fractions (hexane fraction and methylene chloride fraction) were phytochemically investigated using GC/MS technique. The whole of thirty-five compounds were identified and quantified. They are belonging to different classes; twenty-one acetogenins (fat derivatives), six shikimates, five terpenes and one sterol. Beside the characterization of the volatile compounds profile, β-amyrin was isolated and identified using chromatographic and spectral techniques.
The two polar fractions (ethyl acetate fraction and butanol fraction) were isolated and identified by chromatographic and spectral technique. Ethyl acetate fraction was separated on PTLC, silica gel to yield two compounds, trigonotin A which was the first time to be isolated from the plant, in addition to a new sucrose ester of aryldihydronaphthalene type lignin, which we named moltkiopsin A. Butanol fraction was separated by polyamide CC, then purified on PTLC to yield trigonotin C compound, which was the first time to be isolated from the plant.