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العنوان
Effect of maternal serum triglycerides and high density lipoprotein ratio on fetal macrosomia in non diabetic patients/
المؤلف
Qotb, Nourhan Mohamed Abd El Hamid.
هيئة الاعداد
باحث / نورهان محمد عبد الحميد
مناقش / مني توفيق الابياري
مناقش / نرمين سعد البلتاجي
مشرف / نرمين سعد البلتاجي
الموضوع
Obstetrics. Gynecology.
تاريخ النشر
2022.
عدد الصفحات
52 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
28/12/2022
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Obstetrics and Gynecology
الفهرس
Only 14 pages are availabe for public view

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from 65

Abstract

Dyslipidemia is a pregnancy related physiological change that can result in a wide range of maternal and fetal outcomes. Fetal macrosomia is directly associated with plasma lipid changes during pregnancy. These changes occur throughout the gestation, including: TG, TC, and LDL-C levels, increase gradually during gestation and peak before delivery; meanwhile, HDL amounts increase from the first to second trimester with a slight decrease in the third trimester. Maternal serum TGs level to HDL ratio is used as marker for dyslipidemia.
The objective of this work was to study the effect of maternal serum TGs to HDL ratio on fetal macrosomia in non-diabetic cases admitted for delivery at El-Shatby Maternity University Hospital:
The patients were recruited from El-Shatby Maternity University Hospital. 160 Egyptian women participated in the study, group A included (80 cases) pregnant women with macrosomic fetuses, group B included (80 cases) pregnant women with average sized fetuses.
There was statistically significant difference in both groups according to maternal ratio of serum TGs to HDL. There was a statistically significant association between neonatal macrosomia and maternal serum triglycerides alone and TG\HDL ratio but the association between HDL alone and neonatal macrosomia was not statistically significant.
Our study also revealed a statistically significant correlation between high maternal serum TGs, TG\HDL ratio, pre-conceptional BMI, weight increase during pregnancy and parity. There was no statistically significant difference between HDL alone and fetal macrosomia and its relation to maternal characteristics.
A high serum TG\HDL ratio in late pregnancy was strongly associated with an increased risk of fetal macrosomia in non-diabetic women.