الفهرس 
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Abstract
Aim of Work
The aim of the current study is to find retrospectively prognostic parameter difference between breast cancer subtypes Luminal A, Luminal B. and 5-year rates of overall survival (OS), Disease free survival (DFS) in women diagnosed with luminal early-stage breast cancer at clinical oncology department, faculty of Medicine, Beni-Suef University Hospital from Jan 2015 till December 2019.
Patient and Method
This is a retrospective cross-sectional, conducted in the Clinical Oncology Department in Beni Suef Universityfrom Jan 2015 till Dec 2019
Target Population
During the period of data collection all female patients with early stage Luminal A, Luminal B breast cancer attending the department will be included in the study.
Results
There was significant difference between luminal A, luminal B regarding age, as most patients more than 60 yrs old had luminal A breast cancer.There no significantdifferences between luminal A, luminal B regarding DFS,OS but DFS, OS in luminal A was longer,as luminal A is the best prognosis of molecular subtypes. There was significant differences between luminal A, luminal B regarding chemotherapy, which most of luminal A not received chemotherapy, because luminal A breast cancer less benefit of chemotherapy. There was significant association between T3 and younger age less than 40 years but from 40 to 60 and above 60 there was no significant association with T1, 2&3.There was a significant association between ages more than 60 years and lower Ki67.There was significant higher overall survival in patients without comorbitities than patients with DM or HTN or both.