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Abstract The World Health Organization (WHO) declared a pandemic in March of 2020 owing to the severe acute respiratory syndrome coronavirus 2 (Covid-19) outbreak (SARS-CoV-2). Aerosols released while sneezing and coughing are responsible for spreading the disease. High body temperature, cough, runny nose, nasal congestion, trouble breathing, headache, and muscular pains are all symptoms of Covid-19. Ground-glass opacities on CT images, positive polymerase chain reaction results, and clinical symptoms all contribute to a diagnosis. Recent studies have looked at the possibility that lymphocyte counts, C-reactive protein (CRP) levels, homocysteine levels, and D-dimer levels may all be used to predict Covid-19. Covid-19 causes an increase in ferritin levels, which is beneficial since ferritin is involved in the immune response. Elevated ferritin levels may contribute to the initiation of a cytokine storm via their direct immunosuppressive and pro-inflammatory activities. Vitamin D increases the generation of antimicrobial peptides, which help the body’s natural defences against infection, by altering its nuclear receptor. Vitamin D, which is thought to reduce the risk of viral infections through numerous routes, is depleted in patients with viral pneumonia. The most severe cases of Covid-19 were associated with microangiopathy, hypercoagulability, and increased D-dimer values. Human coronaviruses are a common childhood illness, often causing mild to moderate upper respiratory symptoms that resolve on their own. Symptomless or mildly unwell, requiring little in the way of hospitalisation or intensive care, and dying at a low rate, these are the usual clinical results for children infected with SARSCoV-2, as were described during outbreaks of two previous new coronavirus infections during the last two decades. |