الفهرس 
IntroductionandRationaleOnly 14 pages are availabe for public view
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Abstract
Respiratorydistresssyndromeisasevereclinicalsyndromeofacutelunginjuryit occurs in the preterm neonates due to deficiency of surfactant secreted by type IIalveolar cells its incidence is increased due to increase rate of caesarian section ithas seriouscomplications as intracranial haemorrhage, PDA, NEC, pulmonaryhaemorrhage, apnea of prematurity. Bronchopulmonary dysplasia and retinopathyofprematurityarelong termcomplicationsdue to oxygen therapy.
Therefore, this study was performed to assess the efficacy of non-invasiveventilationintreatmentofRDS,whichmayreduceventilator-associatedcomplications.
We enrolled 81 preterm neonates with RDS in a single blind randomizedcontrolled trial study to evaluate the efficacy of non-invasive ventilation, as aprimarytreatmentofrespiratorydistresssyndromeinpretermnewborn,forreduction of short-term complications associated with invasive ventilation. Thestudy population was randomly allocated into three groups regarding to the non-invasive modes of ventilation: group A: NCPAP (n=27), group B: NIPPV (n=27)and group C: HHHFNC (n=27). Our study showed that there was no statisticaldifference among the different group according to gender, mode of delivery, parity,maternaldiseases,antenatalsteroids,surfactantadministration,gestationalage,birthweight, the 1and 5 minutes APGAR score, Down score, and respiratory distressgrade X ray. There was a significant difference between the groups (P value 0.04)according to the pH results after two hours of admission in the NCPAP group.However, there was no statistical difference between the groups according PaO2,PaCO2andLaboratoryresults(HB,WBCs,plateletsandCRP).Theoutcomeresults