الفهرس 
Title : The possible neuroprotective effect of astaxanthin on monosodium glutamate and aspartame induced brain changes in albino rats
ContentsOnly 14 pages are availabe for public view
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Abstract
Food additives are substances added to food to maintain or improve its safety, freshness, taste, texture, or appearance. There are several thousand food additives used, all of which are designed to do a specific job in making food safer or more appealing. WHO, together with FAO, groups food additives into 3 broad categories based on their function. The first group are Flavoring agents which are added to food to improve aroma (e.g MSG) or taste, Enzyme preparations and Other food additives which are used for a variety of reasons, such as preservation, coloring, and sweetening(e.g ASP). Aspartame is an artificial sweetener which is found in more than 6000 food products, while MSG is widely used as a flavor enhancer in the food industry. It has been proved that ASP and MSG induced oxidative stress in different tissues of experimental animals after its chronic administration. On the other hand, AST is antioxidant substances. Therefore, the present study was performed to study the microscopic and morphometric alterations induced by MSG, ASP individually and in combination in cerebral cortex, hippocampus and cerebellum and to demonstrate possible protective effect of AST on those induced changes