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Abstract Back ground: Elevated serum uric acid is more common in women after menopause. There are many serious complications which are associated with increased serum uric acid such as gout, metabolic syndrome, renal calculi and cardiovascular problems. Purpose: The aim of this study was to determine the effect of aerobic exercise on preventing post-menopausal hyperuricemic complications. Subjects and methods: Forty female patients, had elevated serum uric acid levels were selected randomly from Outpatient clinic of Department of Rheumatology and Rehabilitation in Elkasr Eleiny, Cairo university, their ages ranged from 50 to 65 years old and their body mass index (BMI) didn`t exceed 30kg/m2. The participants were assigned into two groups of equal number. group (A) (20 patients) treated by aerobic exercise 3 sessions per week and diet modification for 8 weeks and group (B) (20 patients) treated by diet modification only, for 8 weeks. All patients in both groups were assessed through serum uric acid level test, visual analogue scale (VAS) to measure pain intensity and borg rating of perceived exertion was used to assess functional activity before and after treatment. Rresults: It was revealed that there was a statistically significant improvement in serum uric acid level, pain and physical activity in group (A) than group (B). Conclusion: The effect of aerobic exercise along with diet modification was more effective in reducing serum uric acid level, pain intensity and functional disability than diet modification only in postmenopausal hyperuricemic patients |