الفهرس 
Title : Evaluation of right ventricular functions in patients with ischemic cardiomyopathy by speckle tracking echocardiograph
AbstractOnly 14 pages are availabe for public view
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Abstract
Background Assessment of right ventricular (RV) function has a paramount importance in patients with ischemic cardiomyopathy. Conventional (2D) 2-dimensional determination of RV function is often qualitative. Speckle tracking echocardiography (STE) is a promising tool in assessing regional and global RV deformation in terms of amplitude and timing. We thought to evaluate RV functions and establish the prevalence of RV dysfunction, defined as TAPSE{u2264}16 mm in patients with ischemic heart disease (IHD) and left ventricular (LV) systolic dysfunction, using STE. Methods we prospectively studied 50 patients with the diagnosis of IHD and LV systolic dysfunction (EF< 50%) who underwent trans-thoracic echocardiography. Comprehensive assessment of the RV as regards dimensions (EDA, ESA, basal, mid, longitudinal dimensions, RVOT proximal and distal, and RV free wall thickness), conventional systolic (TAPSE, FAC, S’, RV MPI) and diastolic parameters (E/A, E/E’, DT) were measured. RV Global longitudinal strain (GLS) and free wall RV peak systolic strains (RV FW PSS) as well as LV GLS were measured by using STE. Right and left ventricular peak systolic strain rate (RV SRs, LV SRs) as well as early diastolic strain rate (RV SRe, LV SRe) were also measured. Results There was no agreement between the measurement of RV longitudinal systolic function by TAPSE compared to RV FW PSS (Kappa 0.063, p 0.2). MPI was the only conventional parameter measured by 2D echocardiography that correlated with RV GLS (r = 0.315, p = 0.026). Further evaluation of RV function by strain rate showed that RV SRs was significantly lower (r = 0.631, p < 0.001), and RV SRe was significantly higher (r = -0.346, p = 0.014) in ICM patients having normal RV systolic function by RV FW PSS, considering the unit of systolic strain and strain rate is negative, a negative correlation indicates that the lower parameter correlated, the better the RV function by strain and strain rate and vice versa