الفهرس | Only 14 pages are availabe for public view |
Abstract Intestinal ischemia/reperfusion (II/R) induces a systemic inflammatory response and releases harmful substances that may affect the function and integrity of distant organs such as brain, lung, liver, and kidney. Oxidative stress and inflammatory cytokines are among the key mechanisms of brain tissue damage after intestinal ischemia reperfusion. Therefore improving the redox balance, abating the inflammatory cytokines are the most important goals to attenuate damage after intestinal ischemia reperfusion. Curcumin (CUR), the turmeric is the common name for Curcuma longa, exhibit several pharmacologic properties as anti-inflammatory and antioxidant agent and exert neuroprotective effects in a variety of neurodegenerative disorders including Alzheimer{u2019}s disease, Parkinson{u2019}s disease, and cerebral ischemia by crossing the blood{u2013}brain barrier Moreover, Curcumin is known to play a vital role against oxidative-stress-mediated pathological conditions. , protect biomembranes against peroxidative damage |