الفهرس 
Demographic, clinical and dermatological assessment & therapeutic intervention
ContentsOnly 14 pages are availabe for public view
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Abstract
Background: Pruritus is a frequent and agonizing symptom accompanying various liver diseases, particularly cholestatic disorders. Aim: to evaluate pattern of pruritus among pediatric patients with chronic liver diseases. Methods: This study was carried out at the Pediatric Hepatology Unit, Cairo University Specialized Pediatric Hospital and was designed as a cross-sectional study on 51 patients which their age range from (1-10years) using 12 item pruritus severity scale and 5Ds score to assess response of medical treatment and Children{u2019}s Dermatology Life Quality Index (CDLQI) to measure quality of life in young children and infants with skin affection. Every patient underwent full history, clinical and dermatological assessment using different dermatological scores(5 Ds and12-Item pruritus severity scale to assess severity of pruritusand children{u2019}s dermatology life quality index to assess how their disease affects their lives). Results: 41%of the patients were males and 59% were females. According to 5Ds score, 35% of the patients are classified to severe form of pruritus; according to 12-item pruritus severity scale, 57% had severe form of pruritus and according to children{u2019}s dermatology life quality index, pruritus affect lives of 46.9% of these patients. It was found that 39.2% of patients who diagnosed cholestasis with normal GGT suffered from severe form of pruritus. Local application of coconut oil in addition to strict therapeutic management using cholestramine had a good response to reduce the severity of pruritus