الفهرس 
Title : Formulation of multi-unit tablets combining pulsatile and sustained effects of a model drug
ContentsOnly 14 pages are availabe for public view
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Abstract
Oral drug delivery is the most convenient route of drug administration. More efforts were performed to optimize this route for therapeutic maximization and side effects minimization. Controlled drug delivery was developed to enhance drug performance and increase patient compliance. There are several factors affecting the anticipation of developing oral modified release systems. Such factors are either drug or polymer related. The aim of the present work is to formulate and evaluate controlled release oral dosage forms of etodolac through the manipulation of different formulation parameters to achieve the optimized formulation owning pulsatile and sustained drug delivery. Etodolac was formulated with different polymers (EudragitP® P and HPMC) at different ratios