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العنوان
Synthesis, characterization and applications of some organometallic schiff bases and their metal complexes /
الناشر
Reem Gamal Mahmoud Deghadi ,
المؤلف
Reem Gamal Mahmoud Deghadi
هيئة الاعداد
باحث / Reem Gamal Mahmoud Deghadi
مشرف / Maher Mahmoud Ibrahim Eldessouky
مشرف / Walaa Hamed Mahmoud
مشرف / Maher Mahmoud Ibrahim Eldessouky
تاريخ النشر
2018
عدد الصفحات
398 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
Inorganic Chemistry
تاريخ الإجازة
15/5/2019
مكان الإجازة
جامعة القاهرة - كلية العلوم - Inorganic Chemistry
الفهرس
Only 14 pages are availabe for public view

from 492

from 492

Abstract

Five new organometallic Schiff base ligands that derived from condensation of 2-acetylferrocene with 4-nitro-1,2-phenylenediamine (L¹), 1,8-naphthalenediamine (L²), 3,4-diaminopyridine (L³), alanine (HL₄), 4-aminosalicylic acid (H₂L⁵) and their transition metal complexes with Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) were synthesized and characterized using many analytical techniques such as elemental analyses, molar conductance, mass spectrometry, IR, ¹H-NMR, SEM and thermal analyses techniques (TG and DTG). The complexes had octahedral geometry. In addition, computational studies of the five prepared Schiff base ligands had been carried out using DFT/B3LYP method.The biological activity (antimicrobial and anticancer activity) of the ligands and their metal complexes were also investigated. Molecular docking was used to determine the probable binding mode between the five ligands and their metal complexes with different active sites of various proteins