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العنوان
Synthesis of novel heterocyclic compounds utilizing active methylene reagents and thiols as precursors /
الناشر
Hadeer Mohamed Diab Elhosseny ,
المؤلف
Hadeer Mohamed Diab Elhosseny
هيئة الاعداد
باحث / Hadeer Mohamed Diab Elhosseny
مشرف / Ahmed Helmy Mahmoud Elwahy
مشرف / Ismail Abdelshafy Abdelhamid
مناقش / Hyman Hassan Rehan
تاريخ النشر
2018
عدد الصفحات
154 P. ;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Organic Chemistry
تاريخ الإجازة
16/3/2018
مكان الإجازة
جامعة القاهرة - كلية العلوم - Organic Chemistry
الفهرس
Only 14 pages are availabe for public view

from 249

from 249

Abstract

Part1:A new series of poly(tetrahydrobenzimidazo[2,1-b]quinazolin-1(2H)-ones) was synthesized using a multicomponent reaction of poly(aldehydes), dimedone and 2-aminobenzimidazole in DMF under conventional heating as well as under microwave irradiation.Part 2:The synthetic utility of 3-thioxo-1,2,4-triazin-5-ones 1 and4-amino-3-mercapto-1,2,4-triazin-5(4H)-ones 2 as building blocks for novel bis- and poly(1,2,4-triazines) via alkylation with the corresponding bis- and poly(halo)compounds was investigated. Prediction of the site of alkylationhas been confirmed using spectroscopic data.The reactivity of the novel bis-amines towards aromatic mono- and bis(aromatic aldehyde) has also been investigated.Keywords:Poly(aldehydes),dimedone, 2-aminobenzimidazole,cyclocondensation, Michael addition, poly(alkylation), poly(tetrahydrobenzimidazoquinazolinone), 3-thioxo-1,2,4-triazin-5-one, 4-amino-3-mercapto-1,2,4-triazin-5(4H)-one, alkylation, bis-triazine, poly-triazine, condensation