الفهرس 
Title
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Abstract
Breast cancer is the most common invasive cancer to affect women in the world. It is the second highest cause of cancer death in women after lung cancer. Breast cancer screening remains a subject of intense debate. Mammography has long been the mainstay of breast cancer detection and is the only screening test proven to reduce mortality. Although it remains the gold standard of breast cancer screening, there is increasing awareness of subpopulations of women for whom mammography has reduced sensitivity. Mammography also has undergone increased critical observation for false positives and excessive biopsies, which increase radiation dose, cost, and patient anxiety. Handheld US (HHUS) is widely available and well tolerated. A large multicenter trial has demonstrated that screening with HHUS finds significantly more early-stage breast cancers than screening with mammography alone and has a cancer detection rate of 0.3%-0.5%. However, bilateral whole-breast screening using HHUS is time consuming and has a high number of false positives. In addition, its practicability has been questioned because of the lack of standardized techniques, operator dependence, non-reproducibility, and time required by the radiologist to perform the exams