الفهرس 
Title
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Abstract
Introduction: The aim of the study was to evaluate changes that occur in the retinal layers in systemic lupus erythematosus (SLE) patients using SD-OCT, confirming the value of OCT as an easy, rapid and non invasive imaging technique that can be used in early detection and follow up of retinal involvement in SLE disease. It was performed at the department of Ophthalmology, Kasr Al Ainy hospital, Cairo University in 14 months{u2019} duration. Method: The study was a cross sectional observational, case-control, non-randomized study. It included 77 eyes of 77 individuals divided into two groups; group A (SLE patients), group B (control). All patients had a full ophthalmological examination and OCT assessment of central foveal thickness (CFT), retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thicknesses and all data were correlated to each other. Results: The average CFT in group A was 226.45±26.9, and in group B it was 248.2æ±19.04, with statistically significantly difference (p<0.001). The average RNFL thickness in group A was 108.81 æ±12.41, and in group B it was 113.42æ±4.98, also with a statistically significant difference (p=0.041). As for the average GCC thickness in group A it was 107.67 æ±10.76, while in group B it was 113.52 æ±7.76, which was significantly different (p=0.008). Conclusion: OCT parameters (CFT, RNFL and GCC) are the key parameters that can be used for early detection and follow up of SLE effect on the retina and the optic nerve head