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العنوان
Analytical study of some Ý2-agonists and/or cholinesterase inhibitor drugs /
الناشر
Sherif Mohamed Eid Hassan Awadalla ,
المؤلف
Sherif Mohamed Eid Hassan Awadalla
هيئة الاعداد
باحث / Sherif Mohamed Eid Hassan Awadalla
مشرف / Khadiga M. Kelani
مشرف / Soheir A. Omar
مشرف / Mohamed R. Elghobashy
مشرف / Mohamed K. Abd El-Rahman
تاريخ النشر
2018
عدد الصفحات
178 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الصيدلة
تاريخ الإجازة
1/1/2018
مكان الإجازة
جامعة القاهرة - كلية الصيدلة - Analytical Chemistry
الفهرس
Only 14 pages are availabe for public view

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from 222

Abstract

The thesis represents Analytical and Bioanalytical studies of two drugs; Bambuterol which is a long acting Ý2 agonist and Physostigmine that act as cholinesterase inhibitor. The aim of this work was to develop new simple, accurate, sensitive analytical methods for determination of the under-investigation drugs in their pharmaceutical dosage form and /or biological samples, also to develop a bioanalytical method that depend on the biological activity of some of these drugs. The thesis consists of two Parts; part I, consist of seven sections and Part II, consist of three sections.The use of FTIR , Chemometrics, HPLC and potentiometric analytical techniques can be applied for selective determination and quality control analysis of the interesting drugs in pharmaceutical formulation. Also, the enzymatic kinetics determination can be applied at point of care for screening and prevent respiratory paralysis