الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
3-Chloro-1H-indole-2-carbaldehyde (I) was synthesized according
to the reported procedure and allowed to react with aromatic amines in
ethanol in the presence of piperdine to afford Schiff bases (IIa-c).
Compounds (IIa-c) were converted into 3-chloro-1H-indole-2-
azetidinonyl derivatives (IIIa-c) using chloroacetyl chloride and
triethyl amine in dioxane. Compound (I) was converted into thr
corresponding 3-chloro-1H-indole-3-carbaldehydeoxime (IV) via its
reaction with hydroxyl amine hydrochloride in refluxed ethanol. The
conversion of oxime (IV) to 3-chloro-1-acetyl indole-2-carbonitrile
(V) achieved by the treatment with acetic anhydride. Chlorocyano
compound (VI) was obtained by deacetylation of compound V with
hydrazine hydrate in ethanol .