الفهرس 
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Abstract
Objective: The purpose of this study was to formulate and evaluate the mechanical and physical properties of the experimental nano calcium aluminate-based repair material, then to evaluate of the bone healing process and histological changes after using diode Laser, experimental nano calcium aluminate-based material and biodentine in repairing induced furcal perforations in dogs’ teeth. Methods: The current study composted of two parts, part one (in-vitro study) and part two (animal study).For part one ,A mixture of calcium carbonate and aluminum oxide was used to formulate calcium aluminate phase (CA), tri-calcium-Silicate phase (C3S) was formulated by firing of calcium carbonate and quartz. The produced powders were investigated by X-ray diffraction, then (CA) and (C3S) mixed with water. The produced (CA/ C3S) material was evaluated for ,cytotoxicity setting-time, micro-hardness, dimensional-stability ,solubility and calcium ion release. For part two study, A total of ninety-nine teeth from nine dogs were used. Teeth were divided into six groups according to the evaluation period, each group was subdivided into three subgroups according to the material used and the seventh group represent the control group (intact teeth) . Root canal treatment was performed, furcal perforation was created then sealed with (CA/ C3S), biodentine , Mta and cavit. For the lased group, a diode 870nm laser was employed. Dogs were sacrificed, samples containing the treated teeth prepared for histological examination. Results: For part one of the study, data showed that experimental material has a low cytotoxic effect as the inhibitory concentration inhibit 50٪ after 24 hr.The CA/C3S material mean setting time was (32.70 min ± 0.75) , the mean microhardness was (56.50±7.41VHN), CA/C3S exhibit 0.6٪ expansion after 30 days, experimental CA/C3S showed an increase in weight after 7 days. The calcium ion release increased by time for the material. For part two of the study, the inflammation wasdecreased by time for in all groups except for the group sealed Cavit and lased with diode 870nm, while lowest inflammation records were in the group sealed with the experimental material and exposed to diode laser with total absence (60٪) or mild (40٪) inflammation,CA/C3S repair material in the lased group stimulates the formation of hard tissue over timein 80% of samples at the end of the evaluation periods.There was a significant difference between values measured at different intervals with no cementum formation in all specimens after two weeks, in comparison to cementum deposition in 80% of the cases after three months.there was no statistically significant difference between the tested groups for periodontal ligament regeneration.All the tested groups showed low epithelial tissue invasion at three months interval except for group filled with Cavit and lased with diode 870nm. Conclusion: The experimental (CA/ C3S) material within the limits of this study showed low cytotoxicity, good physical and mechanical properties, good impact on decrease the inflammation , high bone repair capacity, periodontal ligament regenerating.The experimental (CA/ C3S) material had a competitive impact on reduce the inflammation , bone healing, cementum deposition when compared to biodentine and MTA. 870nm diode laser had a good effect in reduce the inflammation process and increase bone repair when combined with the experimental (CA/ C3S) material Keywords: Calcium-aluminate/Tricalcium-silicate,MTA,furcal-perforation,Diode-870nm,biodentine, physical properties and microhardness