الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
In developing countries, rheumatic mitral valve stenosis is still a problem. Its progression leads to left atrial damage, which predisposes to atrial fibrillation, thrombus formation, and decompensated heart failure, all of which substantially modify the prognosis and course of the disease. As a result, left atrium evaluation was shown to be clinically significant in mitral stenosis.
Due to the complexity of the left atrium geometry, currently used techniques like antero-posterior dimensions and 2D echo delivered Left atrium volume have several limitations that are corrected by 3D provided LA volumes. Additionally, functional evaluation with strain echo enables us to evaluate the three physiological functions of the left atrium: the pump, the conduit, and the reservoir.
Thus, the aim of our study was to assess the left atrial functions using 2D speckle tracking echocardiography and 3D transthoracic echocardiography in patients with moderate – severe mitral valve stenosis in comparison to normal healthy subjects
This research comprised fifty patients with moderate to severe rheumatic mitral stenosis and fifty healthy controls. The 3D Left atrial volumes and EF were quantified, and the left atrial 2D speckle tracking echo parameters were generated using dedicated software.
3D LA maximum and minimum volumes indexed to BSA were both significantly higher in MS than in the control group, whereas 3D LA EF was significantly lower in MS than in the control group, both with p 0.001.
LA 2D strain echo parameters reservoir, conduit, and contraction were significantly lower in the mitral stenosis group than in the control group with a p =0.001.
All LA assessment parameters (3D LAVmaxI, 3D LAVminI, 3D LAEF, 2D LASr, 2D LAScd, 2D LASct, 2D LAD, 2D LAVI) correlated with each other with a p <0.01. However, only 3D LAEF, 2D LASr, 2D LAScd, and 2D LASct showed a correlation with the mitral valve area with a p <0.05, but 3D LAVmaxI and 3D LAVminI did not.
Additionally, in the comparison of moderate and severe mitral stenosis subgroups, 3D LAVmaxI and 3D LAVminI did not show any statistically significant differences between the two groups, although 3D LAEF.