الفهرس 
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Abstract
The aim of this work was to assess the role of dynamic contrast-enhanced MRI and diffusion-weighted imaging in the evaluation of non-palpable breast masses by assessing the diagnostic performance of these two modalities against definite pathological diagnoses. This prospective study was carried out on 50 adult female patients who were suspected to have non-palpable breast masses accidentally discovered or suspected by ultrasound and referred to MR units of Radio diagnosis department at Tanta University Hospital over one year starting from August 2020 to August 2022. These patients were excluded: Un-cooperative Patients with mental or behavioral disorders; Presence of cardiac pacemakers, ferromagnetic intracranial aneurysm clips; Claustrophobic patients.; and History of allergy from intravenous contrast media (Gadolinium). All Patients were subjected to the following: 1. Complete history. 2. Full clinical examination. 3. Laboratory investigations: 4. Kidney, and liver function tests, as well as a complete blood picture, were done. 5. Mammogram and breast Ultrasound for 50 patients. 6. Breast Magnetic Resonance Imaging (MRI). It was done in all cases. Discussion 95 The main results of the study revealed that: • Of the 50 patients included in our study, 29 patients (58%) had malignant breast lesions while 21 patients (42%) had benign lesions. The most common malignant pathology was infiltrating ductal carcinoma (59%), followed by Invasive lobular carcinoma (31%), and ductal carcinoma in 10% of the malignant lesions. • For the benign lesions, seroma and fibroadenoma represented 38% and 19% of the benign lesions, respectively, followed by lipoma, fibrocystic changes, and fat necrosis (9.5%, each). • Regarding the Dynamic MRI evaluation of the breast masses 54% of patients had lesions showed ill-defined border, followed by 38 % showed well-defined border, and partially defined border in 8%. & regarding to pattern of enhancement 42 % of cases showed homogenous enhancement, followed by heterogeneous enhancement were found in 48 % & (6, 4%) of cases showed central &peripheral enhancement respectively • Regarding the BI-RADs scores, BI-RADS II lesions were 28%, III were 12%, IV were 6%, and V were 54%. • Regarding the types of dynamic curves, the most common observed curve type was type III (54%) followed by type I (40%) and type II (6%). Type I curve was the most exclusive to benign lesions and it has a 90% sensitivity for benign lesions. Also, the type III curve was most exclusive to malignant lesions with a 90% sensitivity. Discussion 96 • Diagnostic performance of DCE-MRI for malignant lesions had a sensitivity of 89.6% and a specificity of 95.2% and for benign lesions had a sensitivity of 90.5%. and a specificity of 96.6%. • Diagnostic performance of DWI MRI for malignant lesions had a sensitivity of 93.1% and a specificity of 71.4%.