الفهرس | Only 14 pages are availabe for public view |
Abstract The results of this study showed that: •There was no statistically significant difference in the age and sex distribution between the cases in the different study groups. •There were no statistically significant differences were found regarding presence of DM or hypertension between studied groups. •All cases had positive HCV antibodies, while all controls were negative HCV antibodies. •Albumin and platelets were significantly lower in compensated and decompensated cases when compared to control groups, while no significant differences were found between compensated and decompensated groups. •CRP titer, bilirubin level, WBCs count, ALT, creatinine level and INR showed a statistically significant increase in the compensated and decompensated cases when compared to control groups, as well as in decompensated when compared to compensated groups. •AST showed significantly higher levels, in patients with decompensated cases when compared to control groups, as well as in decompensated when compared to compensated groups, while no significant difference was found regarding AST level between compensated and control groups. •Serum procalcitonin level showed a statistically significant increase in the compensated and decompensated cases with sepsis when compared to control groups, while no significant differences was found between compensated and decompensated groups. •There was a statistically significant higher incidence of ascites and pleural effusion in decompensated compared to compensated group. •Decompensated cases with sepsis showed significantly higher MELD, higher frequency of B and C Child classes, and mortality rate when compared to compensated groups. •Among compensated as well as decompensated groups, higher PCT level was observed in those admitted to ICU when compared to those were did not. •Among compensated as well as decompensated groups statistically significance, higher PCT level was observed in those who died during the study period when compared to those did not. •PCT showed significant positive correlations with CRP, bilirubin, WBCs, ALT, AST, INR, creatinine, length of hospital stay, as well as significant negative correlations with platelet count. •Higher PCT, and longer hospital stay were associated with risk of ICU admission in univariate regression analysis. However, in multivariable analysis, only higher PCT level was considered independent predictor of ICU admission. •Higher PCT, AST, longer hospital stay were associated with risk of death in univariate analysis. However, in multivariate analysis, only higher PCT level was considered independent predictor of higher death prediction. PCT revealed high diagnostic accuracy in differentiating control group from compensated and decompensated cases with sepsis, but it didn’t accurately differentiate the compensated from the decompensated cases. |