الفهرس 
Pathology of cancer of unknown primaryOnly 14 pages are availabe for public view
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Abstract
Objectives: Our aim in this study was to evaluate the efficiency of combined positron emission tomography and computed tomography (PET/CT), in the detection of the primary tumor origin in patients with metastatic osseous lesions of cancer of unknown primary origin (CUP).
Methods: PET/CT was performed for 50 patients with CUP. These patients presented with metastatic osseous lesions that were pathologically proven, radiologically , and/or clinically suspected osseous metastatic lesions with no detected primary site .
Results: The number of patients with true positive primary tumor sites was 42 (84 %), with no false positive results , 5 patients with true negative results (10%) and 3 patients with false negative results (6 %). The sensitivity was 93.3 %, specificity was 100 % . Our positive predictive value in this study was 100 % and our negative predictive value for this study was 62.5 %.
Conclusions: This study showed an advantage of PET/CT in the detection of the site of the primary tumor in patients diagnosed with CUP.