الفهرس 
List of figuresOnly 14 pages are availabe for public view
 |  | from | 71 |  |  |
| | | from | 71 | | |
Abstract
This study on non-keratoconic thin corneas and keratoconus subclinical or with mild evolution demonstrates that various tomographic (elevation, pachymetry, and BAD) parameters and topometric indices derived from Pentacam Scheimpflug tomography can effectively discriminate these eyes. CT at apex, thinnest CT, IVA, IHD and PE differences seemed to be best in discriminating normal thin cornea from subclinical keratoconic eyes. However, the specificity levels of these parameters were relatively limited and comprehensive analysis of these parameters may provide useful information for improving the accuracy of subclinical keratoconus diagnosis. Such findings support the previous reports on the usefulness of Scheimpflug images in assessing subclinical keratoconic eyes, which are the main parameters that discriminate eyes with early keratoconus from normal thin corneas. Diagnostic ability of tomographic parameters increased significantly when comparing normal thin cornea eyes from mildest form keratoconus eyes. Posterior elevation differences showed the excellent AUROCs with 100% sensitivity and 100% specificity for this purpose. These findings simplify the selection of patients for refractive surgery and could have important implications to prevent keratectasia in patients seeking refractive surgery.
In addition, the combination of corneal tomography and other keratoconus detection tools, such as corneal biomechanical testing [69] and corneal thickness analysis, [80] increase the ability to differentiate eyes with subclinical keratoconus from normal corneas. Also, the use of the combination of a variety of parameters based on new geometric approach based on the analysis of the cornea as a solid with a specific volume is highly sensitive and specific for an accurate detection of incipient keratoconus, and these additional testing should be the subject of future studies on thin corneas.