الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Testosterone regulate nearly every component of erectile function also modulate time of erectile process.
Total testosterone is determined mainly by level of SHBG. Normal man has forty-four percent (44%) of Total Testosterone is bound to SHBG, two percent (2%) is FT and fifty-four percent (54%) flows bound to albumin and other protein. Bioavailable T include all the non SHBG.
SHBG levels increase with age and decrease with obesity due to high insulin resistance that result in higher levels of insulin which lead to suppressing hepatic creation of SHBG.
There are association between little serum level of testosterone, T2DM with obesity and insulin resistance as dominant topographies. Low testosterone leads to decrease in mass of the muscle and increase in lipid bulk which lead to increase resistance to insulin. As well as stem cell properties, testosterone reduced resistance to insulin by increasing lipolysin induced by catecholamines, and dropping activity of lipoprotein lipase and uptake of triglyceride in abdominal tissue of the human. Hyperglyceridemia result in elevated FAA and decreased clearance of insulin.
So, by endorsing myogenes and lipolysis s, testosterone may result in better resistance to insulin.
The study goal is to associate FT, TT and SHBG among obese non-diabetic and obese diabetic and to assess DM as a risk factor for HH also to estimate correlation of low T and insulin resistance by (HOMA_IR).
The study includes 40 obese diabetic man and 40 obese non diabetic man all with BMI>30Kg/m2 and aged from 19 to 45 years.
The whole members were exposed to physical examination, history taking and measurement of FPG, fasting insulin level, HbA1c, serum creatinine, estimated GFR, serum albumin, TT, SHBG and FT.
The study showed that TT, FT, SHBG, is significant decrease in group A while, IR, FPG and HBA1c is significant increase in group A. TT has a significant positive correlation with SHBG in both groups while FT has a significant positive correlation with SHBG in group A. TT, FT has significant negative correlation with IR, FPG and HBA1c in both group. TT, FT has a significant negative correlation with duration of DM.