الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
ICU-acquired weakness (ICUAW) is considered to show illnesses or managements happening in the ICU. Currently, in order to diagnose ICU-AW it must be qualified by multiple evaluations using the six points of Medical Research Council (MRC) score, which is generally, the reliable standard score for characterizing the degree of ICU-AW.
Soft tissue ultrasound is a reliable approach to follow up the extent of myopathy and muscular changes since admission to ICU. Nevertheless, the relation between other muscle parameters detected by ultrasound and ICU-AW remains unclear.
This work aimed to assess the role of ultrasound as an early predictor of myopathy in critically ill patients and its correlation with the MRC scale for muscle strength.
The study included 50 critically ill patients admitted to the Critical Care Medicine Department in Alexandria University Hospitals according to sample size calculation. Informed written consent was taken from all patients or next of kin and approval of the medical ethics committee of Alexandria faculty of medicine before conducting the study. All included patients were followed up for 28 days.
In the current study, the patients’ age ranged from 18 to 82 years with a mean ± SD of 61 ± 16.12 years. Most of the patients were males (62%). Most common presentation was UTI (18%), and a similar percentage in DFI. Followed by hematological disease (16%), renal diseases (14%), and hepatic diseases (12%), and the least frequent were HTN and bloodstream infection, each of them in only 2% of patients.
Mean SBP was (122.36 ± 20.40), while mean Diastolic BP was (78.06 ± 14.14). Mean heart rate was 95.04 ± 32.51, the mean respiratory rate was (21.4 ± 6.5) and the mean temperature was (37.09 ± 1.25).
Mean Hb level in the study sample was (10.11 ± 2.65), mean platelet count was (187.10 ± 96.43). The mean Serum urea and creatinine were (85.88 ± 56.44), and (1.58 ± 1.71) respectively. Mean Sodium level was (135.82 ± 12.30), while the mean potassium level was (3.91 ± 0.75), and the mean Calcium level was (9.12 ± 0.50).
The median Glasgow coma score was 15, ranging from 14 to 15, and the median APACHE-II score was 15 ranging from 11 to 24.
In the current study, the MRC scale for muscle strength at follow-up was statistically significantly lower than that on admission (median of 31 vs 49, p<0.001), indicating a negative impact on the state and function of skeletal muscles with a long length of stay in ICU.