الفهرس 
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Abstract
The thesis is composed of two parts : Part A : Development and validation of spectrophotometric and HPLC methods for simultaneous determination of Loratadine and Dexamethasone mixture. This part consists of three chapters : Chapter I : Introduction. This chapter presents a general introduction about the combination dosage forms, their advantages and different spectrophotometric methods for their determination. Different UV spectrophotometric methods are discussed with emphasis on those methods that were used to analyze mixtures selected in the thesis. This chapter also describes introduction and review of literature about analytical methods for assay of Loratadine and Dexamethasone. Chapter II: Simultaneous determination of Loratadine and Dexamethasone by ratio derivative spectrophotometry (RDM) and ratio subtraction (RSM) coupled with extended ratio subtraction method (EXRSM).The thesis is composed of two parts : Part A : Development and validation of spectrophotometric and HPLC methods for simultaneous determination of Loratadine and Dexamethasone mixture. This part consists of three chapters : Chapter I : Introduction. This chapter presents a general introduction about the combination dosage forms, their advantages and different spectrophotometric methods for their determination. Different UV spectrophotometric methods are discussed with emphasis on those methods that were used to analyze mixtures selected in the thesis. This chapter also describes introduction and review of literature about analytical methods for assay of Loratadine and Dexamethasone. Chapter II: Simultaneous determination of Loratadine and Dexamethasone by ratio derivative spectrophotometry (RDM) and ratio subtraction (RSM) coupled with extended ratio subtraction method (EXRSM).