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العنوان
Synthesis of some functionalized heterocycles and study of their chemical reactivity /
الناشر
Mohamed Gamal Mohamed Abdelrahman ,
المؤلف
Mohamed Gamal Mohamed Abdelrahman
هيئة الاعداد
باحث / Mohamed Gamal Mohamed Abdelrahman
مشرف / Said Ahmed Soliman Ghozlan
مشرف / Ismail Abdelshafy Abdelhamid
مشرف / Amr Mohammed Abdelmoniem
مناقش / Hyman Hassan Rehan
تاريخ النشر
2020
عدد الصفحات
84 P . :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Organic Chemistry
تاريخ الإجازة
1/11/2020
مكان الإجازة
جامعة القاهرة - كلية العلوم - Organic Chemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

This thesis consists of an introduction and two original parts. In the first part cyclic enaminone and cyanoacetamide derivatives with incorporated sulfamethoxazole moiety were prepared. Their reactions with arylidenemalononitrile derivatives in ethanol or pyridine/piperidine at reflux yielded the corresponding hexahydroquinoline and 6{u2010}amino{u2010}2{u2010}oxopyridine{u2010}3,5{u2010}dicarbonitrile derivatives incorporating sulfamethoxazole. In the second part, one-pot three-component cyclo-condensation reaction of bis(indole-2,3-diones) containing ether-amide or ester-amide linkages with 6-aminouracil in boiling acetic acid afforded tetrakis(6-aminopyrimidine-2,4-diones) or bis(pyrido[2,3-d:6,5-d’]dipyrimidines) depending on the reaction conditions. All the structures were confirmed by the structural and elemental analysis