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العنوان
Assessing the auditory cortical plasticity in presbycusis using the P3 late evoked potential /
الناشر
Zainab Tarek Sayed Abdelaleim ,
المؤلف
Zainab Tarek Sayed Abdelaleim
هيئة الاعداد
باحث / Zainab Tarek Sayed Abdelaleim
مشرف / Mostafa Elkhousht Mahmoud Mourad
مشرف / Abeir Osman Dabbous
مشرف / Hussien Sherif Mohammad Hamdy
تاريخ النشر
2020
عدد الصفحات
157 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الحنجرة
تاريخ الإجازة
5/10/2020
مكان الإجازة
جامعة القاهرة - كلية الطب - E.N.T
الفهرس
Only 14 pages are availabe for public view

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from 191

Abstract

Background: Aging and hearing loss both affect the central auditory pathway. Objective:To determine the extent of cortical plasticity and reorganization in response to auditory deprivation in presbycusis, using P3 at the edge frequency of slopingsensorineural hearing loss(SNHL). Methods: 20 elderly patients with high frequency SNHLwere compared to 20 age-matched controls and to 20 adult controlswith normal hearing threshold level. P3 at small frequency changes between the common and rare stimuli (20 % &5 % &2%)above the edge frequencyof hearing loss,word discrimination score (WDS) and Speech in noise (SPIN) test at SNR 0 &-10 were done. Results:The elderly controls had a significant smaller P3 amplitude especially in 20 % higher change condition, and increased P3 latency at 2 % condition only than the adult controls, reflecting effect of aging on P3.A statistically significantly Larger P3 responses were detected in response to small frequency changes in the Patients group compared to the elderly controls groupwhile the amplitudeswere comparable to the adult controls. Thiscould be either due enhanced cortical representation of frequency at the edge frequency of the high frequency SNHL or due to the increased loudnessof the rare stimulus frequency than that of the edge frequency, adding loudness difference to the frequency difference between rare and common stimuli