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العنوان
Metabolomics in some microalgae and cyanobacteria with an emphasis to their applications /
الناشر
Eman Atef Ibrahim Mohamed Eelfayoumy ,
المؤلف
Eman Atef Ibrahim Mohamed Eelfayoumy
هيئة الاعداد
باحث / Eman Atef Ibrahim Mohamed EL- Fayoumy
مشرف / Sanaa Mahmoud Metwally Shanab
مشرف / Emad Ahmed Ahmed Shalaby
باحث / Eman Atef Ibrahim Mohamed EL- Fayoumy
تاريخ النشر
2020
عدد الصفحات
286 , (36) P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
علوم النبات
تاريخ الإجازة
11/8/2020
مكان الإجازة
جامعة القاهرة - كلية العلوم - Botany & Microbiology Department
الفهرس
Only 14 pages are availabe for public view

from 394

from 394

Abstract

In this study, six microalgal species (Chlorella vulgaris, Dictyochloropsis splendida, Muriella sp., Nostoc muscorum, Anabaena oryzae and Nostoc linckia) were screened for Antioxidant activity and their phytochemicals. The antioxidant activity and bioactive compounds of C. vulgaris and N.linckia were significantly higher than those of the other tested species (p< 0.05) so they were selected for further studies in this thesis. Furthermore, the effect of stress culture conditions on the growth, phytochemicals, antioxidant enzymes, antioxidant, anticancer, antimicrobial, antiviral activities and Peroxide value of sunflower oil of promising microalgal species extracts were studied. Interpretation and identification of active ingredients separated from promising fractionated extracts (by using chromatographic and spectroscopic analyses) as well as determination of their antioxidant and anticancer activity. (2E,7R,11R){u2010}3,7,11,15{u2010}Tetramethyl{u2010}2{u2010} hexadecenol was identified by chromatographic and spectroscopic methods as well as determination of its antioxidant IC50 (10.59 og/ml) using DPPH radical method and anticancer IC50 (4.38 og/ml) against Hela cell line as a promising cell line Also, evaluation of its effect upon gene expression of Hela cell line was performed