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Abstract Statement of problem: Maxillary sinus may have some anatomical variations; one of these is the gothical arch in the sinus floor, the maxillary sinus septum. It was noted that septal presence during sinus lift procedures might cause sinus membrane perforation leading to greater consequences as graft migration with concomitant graft failure and sinus infection. Moreover, diagnostic methods for verification of sinus disorders, as endoscopy, may be hindered due to septal presence. These concerns have led to a different attitude towards the maxillary sinus and its anatomical variations.Aim of the study : To assess the anatomical variations (prevalence, location, orientation, origin, morphology and height) of the maxillary sinus septa in a sample of Egyptian population using 3D cone beam computed tomography. Materials and method: This cross-sectional study evaluated 111 maxillary sinuses using cone beam computed tomography. Presence of septa, location, orientation, origin, morphology and height were evaluated and recorded. Inter and intra observer agreement were done using Kappa statistics.Results: The prevalence of septa was 33.3% in this study. Analysis of the location of the septa revealed that 39.5% were in the middle, 37.2% in the anterior and 23.2% in the posterior areas. Among all septa, the majority of the maxillary sinus septa traversed the sinus in a buccopalatal direction (76.7%). The mean height of vertical septa was 7.21 mm ± 5.02 mm, while the horizontal septa presented at a mean level of 13.09 ±3.6 mm from the floor.Conclusion: Maxillary sinus septa can jeopardize the oral and maxillofacial and ENT surgeons{u2019} plans astoundingly if not well assessed. Fortunately, pre-operative planning using CBCT can be very fruitful in determining the unique septal expression in every subject |