الفهرس 
Absolute neutrophil count in suspected and proven cases of neonatal sepsis
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Abstract
Background: Despite improved neonatal care over the past decades, infections remain common and sometimes life-threatening in neonates admitted to the neonatal intensive care unit (NICU). The diagnosis of sepsis in neonates is difficult because of its non-specific signs and symptoms, and frequent co-morbid conditions that can mask or accompany sepsis. The aim of work was to investigate the value of absolute neutrophil count (ANC) and immature /total neutrophil (I/T) ratio, in establishing the early diagnosis of neonatal sepsis in order to achieve early and proper management of these cases. Methods: This case control study was done on 99 newborns divided into 3 groups: group -1 (38 newborns): proven neonatal sepsis, group- 2 (31 newborns): probable neonatal sepsis and group -3 (30 newborns): controls. All patients in the study were subjected to adequate history taking, full clinical examination, complete blood count including (absolute neutrophil count (ANC) and immature/total neutrophil count (I/T ratio)), C - reactive protein (CRP) and blood culture. Results: ANC was not significantly different across the three groups (p value =0.1). Whereas I/T ratio was significantly different across groups (p value =0.01). Conclusion: ANC didn{u2019}t differentiate infected group from both suspected and negative group. I/T ratio was significantly higher in proven sepsis group than negative group but not in suspected group