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العنوان
Red cell distribution width as a marker of nephropathy in type 1 diabetes mellitus /
الناشر
Nehad Mohammed Mohammed Abdelmageid ,
المؤلف
Nehad Mohammed Mohammed Abdelmageid
هيئة الاعداد
باحث / Nehad Mohammed Mohammed Abdelmageid
مشرف / Khaled Mohamed Salama
مشرف / Yomna Mousa shaalan
مشرف / Khaled Mohamed Salama
تاريخ النشر
2019
عدد الصفحات
72 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
19/2/2020
مكان الإجازة
جامعة القاهرة - كلية الطب - Pediatrics
الفهرس
Only 14 pages are availabe for public view

from 93

from 93

Abstract

Background: Globally, type 1 diabetes is increasing both in incidence and prevalence, with overall annual increases in incidence of about 2{u2013}3% per year Despite the usage of insulin in the treatment, this disease is still associated with increased morbidity due to cardiovascular, renal and nervous system complications. Usage of RDW as marker for early diagnosis of renal complications was reported by some authors. Aim of work:The aim of this study is to assess usefulness of RDW measurement in children with poorly controlled Type 1 DM and prediction of the decline of the renal function and if there is a superiority over old methods. Methods: This case control study was done in the pediatric endocrinology outpatient clinics in New children hospital_Cairo University. It was conducted on 60 patients aged 5_ 18 years suffering from T1DM for more than 2 years and 30 healthy controls who attend outpatient clinics for routine care. Results: microalbuminuric diabetic children had significant increases in HbA1c (P<.001), healthy children had a statistically significantly lower RDW than diabetic children (normoalbuminuric and microalbuminuric children) (P=.006), there is no statistically difference between RDW in normo-albuminuric and micro-albuminuric diabetic patients (P>.05). Conclusion: RDW can not be used as a marker of early kidney affection in type 1 diabetes mellitus