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Abstract Medicinal plants are considered as one of the essential sources of life-saving drugs for the majority of the world’s population. In-vitro regeneration holds enormous prospective for the production of high-quality plant-based medicine. Natural products as spices and herbs contribute in the scientific literature to conflicts about the precise role of diet and several diseases as cancer prevention. Euphorbia cuneata (EP) and Solenostemma argel (SA) are considered as an imperative medicinal plants and has been used for centuries in the kingdom of Saudia Arabia, Jordan, Africa - Guinea, Togo, Benin, Nigeria and Egypt, As the holistic system of medicine originating from Africa. Euphorbia cuneata (EP) and Solenostemma argel (SA) are of the great importance due to thier various phytochemical constituents as phenolic compounds. There were also well known due to thier important medicinal uses for example acetyl choline-like action with muscarinic and nicotinic activities on isolated ileum of rabbit, spasmolytic, diuretic, increase capillary strength anti-leukemic, anti-inflammatory, analgesic and decrease the release of prostaglandin. Other researches noticed irritant and pro-inflammatory effect. |