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Abstract This combined retrospective and prospective cohort study was carried out from 1 April 2020 to 31 October 2021 at Minia University, isolation hospitals, and maternity hospitals. All patients were admitted to labor and delivery, including those who tested positive for SARS-COV-2 at any point during pregnancy. The study’s recruitment of patients from various isolation hospitals was authorized by the Egyptian Ministry of Health and the Obstetrics and Gynecology Department’s Ethical Board. All SARS-COV-2 positive patients were included in this research, and they were compared 1:2 to randomly chosen controls who had a negative SARS-CoV-2 test result. Here, 373 instances were investigated, and after applying inclusion and exclusion criteria, the cases were divided into two groups: 115 cases of positive PCR results for covid-19 patients. 230 instances were among the non-Covid-19 patients in the other group. In order to investigate the link between COVID-19 and preeclampsia, hypertensive diseases were identified in accordance with accepted criteria. This research included detailed information on the patients’ present and past lives, including their age, BMI, gestational age, history of preeclampsia during current or prior pregnancies, and comorbid conditions such obesity, cardiovascular disease, and renal illness. Complete studies that support the COVID-19 infection PCR diagnosis. complete blood count and lymphopenia as described. increased D-Dimer coagulopathy markers elevated CRP, reported S. ferritin, and further liver and renal function testing. Findings from the CT as opaque ground glass. It was discovered that there was a significant rate of maternal and neonatal morbidity and death linked with SARS-COV-2 infection. This study demonstrates a strong association between renal disease and hypertension with the development of PE in COVID-19 patients. For hypertension (OR = 22.6, CI = 6.02) and for renal (OR = 9.75, CI = 1.05-90.64) with a significant P value of 0.045. Maternal complications were reported as ARDS, HELLP syndrome, impaired liver and renal functions linked to maternal mortality. In this research, the maternal death rate rose for the group of COVID-19 patients with PE by a percentage of 41.6 percent, compared to 16.4 percent for the group of COVID-19 patients without PE. Low birth weight, early newborn mortality, RD, IUFD, and IUGR are among the documented neonatal problems. No documented vertical transmission exists. |