الفهرس 
Title : Remineralization potential of innovative biomimetic material versus casein phosphopeptide- amorphous calcium phosphate in caries white spot lesions : A randomized clinical trial
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Abstract
Aim: The current study was conducted to compare between reminerlization potential of innovative biomimetic material versus casein-phosphopeptide/amorphous-calcium phosphate in caries white spot lesions. Methodology: in split mouth design, white spot lesions in anterior teeth of post orthodontic debanding patients received randomly two types of remineralizing agents, either clinpro tooth crème or MI paste plus, both materials were applied according to the manufacturer{u2019}s instructions. White spot lesions were evaluated at base line one month and after 3, 6 months follow up periods by two blinded assessors to assess patient satisfaction using VAS score and color change by Vita Easyhshade. Results: One-way ANOVA followed by post-hoc Tukey{u2019}s test showed that within each remineralizing agent, there was no statistically significant difference in L* mean values between different evaluation time periods. Independent Student-t test showed that at each evaluation time, there was no statistically significant difference in L* mean values between both remineralizing agents.Two-way ANOVA showed that the two independent variables 2remineralizing agent3 (P<0.004) and 2evaluation time3 (P<0.0001) had asignificant effect on patient satisfaction. However, their interaction (P=0.916) showed no significant effect on patient satisfaction. T6 revealed the significantly highest VAS mean values; followed by T3; then T0 and T1 which were statistically similar but vii at each evaluation time, there was no statistically significant difference in VAS mean values between both reminerailizing agents